Our approach to bioresistance

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The global biosecurity landscape is changing rapidly. Changes to natural ecosystems, global travel and the potential misuse of AI require greater vigilance, but AI is also a key tool in our response. We need pioneering AI models and the scientific advances they enable to address these challenges and assist make society more resilient to events such as future epidemics.

Today Google DeepMind i Isomorphic laboratories they share ours a common approach to biological resilience.

Our work is twofold – to prevent our models from being misused by threat actors, and to empower governments, scientists, biosecurity experts and our teams to employ these technologies to build a more resilient world.

Over the last 12 months, we have established more than 15 partnerships with governments, biosecurity organizations and research groups to prevent threat actors from misusing our models, quickly detect modern disease outbreaks, and respond quickly and effectively.

As part of our biological resistance program

We believe that society must leverage the growing capabilities of artificial intelligence to combat infectious diseases and prepare for future epidemics.

Breakthroughs like Google DeepMind’s AlphaFold, which maps the 3D structures of almost all known proteins; Powered by Isomorphic Labs AI Drug design engine (IsoDDE), which provides the real-world accuracy required to navigate modern biological systems with unprecedented precision; and AlphaGenome, which shed airy on genome function, radically change the balance. Instead of simply responding to natural epidemics or security threats, we can now employ these smart systems to assist scientists design proactive defenses, accelerate therapeutic discovery, and protect the global health ecosystem with greater speed and precision.

With this in mind, we share our AI models and agents with trusted partners to support progress in three key areas: prevention, detection and response. Here are some examples:

To prevent:

To ensure that our models, like Gemini, are unthreatening and useful to experts, we follow a four-step security process: threat modeling, assessments, mitigation and monitoring.

We work closely with internal biologists, security experts and external partners to understand potential threats, test our models against them, and build strong defenses.

Additionally, we are working to adapt our SynthID watermarking technology to biology, which could assist DNA synthesis providers screen potentially risky biological sequences generated by AI.

Detect:

We assist make pathogen surveillance more cost-effective. For example, our AlphaEvolve agent can optimize the algorithms used to create and analyze metagenomic sequencing data, helping detect modern outbreaks faster. This optimization allows for faster and more exact DNA analysis, making it cheaper to track diseases around the world on a gigantic scale.

We are also exploring how technologies such as AlphaGenome and Protein function annotation can be used to detect and characterize pathogens from sequence data, identifying modern patterns and emerging threats faster than conventional methods.

React:

Building on AlphaFold’s scientific impact, we provide trusted researchers with access to the latest Google DeepMind artificial intelligence systems to accelerate the design of vaccines and other countermeasures to both known and emerging threats.

To support government and non-profit organizations during modern epidemics, Isomorphic Labs has established a specialized unit tasked with rapidly deploying a drug design engine to design medical countermeasures that could address both naturally occurring pandemics and the potential threats arising from the misuse of advanced artificial intelligence. Collaborating with governments and health authorities around the world to develop a variety of diagnostic and therapeutic strategies enables the Isomorphic Labs Drug Design Engine to have a real impact on biological immunity.

This is a intricate, long-term effort that is part of our broader approach to managing potential chemical, biological, radiological and nuclear (CBRN) threats, consistent with the proactive mitigation measures and stringent assessment protocols included in our Border Security Framework.

We are committed to being open and collaborative – with biosecurity labs, governments and the broader scientific community – to ensure AI is developed and deployed responsibly to assist protect against one of the greatest threats to society.

To learn more about our work and our call for modern partnerships, see this article full update on our approach.

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